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WASHINGTON?? Defense Secretary Leon Panetta is acknowledging publicly for the first time that a Pakistani doctor provided key information to the U.S. in advance of the successful Navy SEAL assault on Osama bin Laden's compound last May.
Panetta told CBS's "60 Minutes," in a profile to be broadcast on Sunday, that Shakil Afridi helped provide intelligence for the raid on bin Laden's compound in Abbottabad, Pakistan.
Afridi ran a vaccination program for the CIA to collect DNA and verify bin Laden's presence in the compound.
He has since been charged by Pakistan with treason .
Panetta said he is "very concerned" for the doctor.
'What the hell's going on'?
Panetta also told "60 Minutes" that he remains convinced that someone in the Pakistani government must have had an idea that a person of interest was in the compound.
Report: CIA ran vaccine ruse to get bin Laden's DNA
"I personally have always felt that somebody must have had some sense of what ... what was happening at this compound. Don't forget, this compound had 18 foot walls ... It was the largest compound in the area. So you would have thought that somebody would have asked the question, 'What the hell's going on there?'" Panetta told the show.
Slideshow: After the raid: Inside bin Laden's compound (on this page)He added that he has no proof that Pakistan knew it was bin Laden.
The Pakistani government had hoped to resolve the Afridi matter quietly, once media attention died down, perhaps releasing him to U.S. custody, according to two Pakistani officials.
Interactive: A timeline of Osama bin Laden's life (on this page)They requested anonymity because the investigation into charges the doctor behaved treasonously was ongoing.
The Associated Press contributed to this report.
Source: http://www.msnbc.msn.com/id/46173360/ns/world_news-south_and_central_asia/
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LOS ANGELES ? When your dinner party guests include Brad Pitt, George Clooney, Kate Winslet and Glenn Close, and the whole affair is televised live, it can take months to plan the menu. That's why the team behind the Screen Actors Guild Awards began putting together the plate for Sunday's ceremony months ago.
It was still summer when show producer Kathy Connell and executive producer and director Jeff Margolis first sat down with chef Suzanne Goin of Los Angeles eatery Lucques with a tall order: Create a meal that is delicious at room temperature, looks beautiful on TV, is easy to eat and appeals to Hollywood tastes. Oh, and no poppy seeds, soups, spicy dishes, or piles of onions or garlic.
"It can't drip, stick in their teeth or be too heavy," Connell said. "We have to appease all palates."
The chef put together a plate of possibilities: slow-roasted salmon with yellow beets, lamb with couscous and spiced cauliflower and roasted root vegetables with quinoa. There was also a chopped chicken salad and another chicken dish with black beans.
To ensure the dishes are both tasty and TV-ready, Connell and Margolis, along with the SAG Awards Committee and the show's florist and art director, dined together at this summertime lunch on tables set to replicate those that will be in the Shrine Exposition Center during the ceremony. The pewter, crushed-silk tablecloths and white lilies you'll see on TV Sunday were also chosen months ago.
The diners discussed the look of the plate, the size of the portions and the vegetarian possibilities.
"We'd like the portions a little larger," Connell told the chef.
"And a little more sauce on the salmon," Margolis added.
Come Sunday, it's up to Goin to prepare 1,200 of the long-planned meals for the A-list audience.
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NEW YORK (AP) ? Chevron Corp. said Friday that its profit slipped by 3.2 percent in the fourth quarter as its refineries struggled to pass on the higher cost of crude oil.
The San Ramon, California, oil giant reported net income of $5.12 billion, or $2.58 per share, in the final three months of 2011. That compared with $5.3 billion, or $2.64 per share, in the same part of 2010. Revenue increased 11.9 percent to $60 billion.
The net income fell short of Wall Street forecasts of $2.86 per share, according to FactSet. Shares dropped $3.26, or 3.1 percent, to $103.33 in morning trading.
Chevron, the second-largest U.S. oil company behind Exxon Mobil Corp., said that oil and natural gas production declined in the quarter due to a rash of slowdowns in its global operation. Production fell for the entire year as well, though the company says it should rebound slightly in 2012.
Production from Chevron wells dropped, from the U.S. to Kazakhstan. One of the biggest concerns for the company going forward is its operation in Brazil, where an offshore oil leak put Chevron in the crosshairs of the Brazilian government.
Regulators in Brazil forced Chevron to shut down one of its offshore production wells in December, and prosecutors are seeking $10.6 billion in damages. Chevron also has voluntarily suspended plans to further explore the country's oil-rich offshore region.
Profits from Chevron's exploration and production business increased, despite weaker production, as the company sold oil at higher prices. International natural gas prices also rose in the quarter.
Chevron's refining business struggled, however, as falling prices for retail gasoline and other fuels made it harder to pass along higher oil costs to customers. Chevron's U.S. refining operations lost $204 million from October to December, compared with a profit in the 2010 quarter. International refining profits fell by 46.4 percent.
For the full year Chevron earned $26.9 billion, or $13.44 per share, compared with $19 billion, or $9.48 per share in 2010. Annual revenue increased 23.3 percent to $253.7 billion.
Earlier in the week, ConocoPhillips reported a 66 percent increase in quarterly earnings, though much of that came from the sale of a pipeline and other assets. Occidental Petroleum Corp. reported a 35 percent jump in quarterly profits as it increased production and sold crude oil for higher prices.
ExxonMobil releases its fourth-quarter and annual financial results on Tuesday.
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BISHKEK, Kyrgyzstan ? More than 1,000 prisoners in Kyrgyzstan have sewn their lips together, a grotesque act inmates describe as a protest of their dismal conditions, but which authorities blame on organized criminal gangs who resent attempts to break the power they wield in prisons.
Kyrgyzstan, a poor ex-Soviet nation of 5.3 million, holds around 7,600 inmates in its detention centers. The buildings are notoriously crowded and disease-ridden, and they have not escaped the reach of powerful criminal syndicates who also threaten the stability of the country, which hosts a key U.S. air base.
Over the years, prisoners have staged numerous protests ? until Saturday, the vast majority of the prisoners were on a 10-day-long hunger strike. But the sewing of lips has been one of the most unusual and brazen ways to bring attention to the prisoners' plight.
An Associated Press reporter who was allowed to visit a pre-trial detention facility recently saw several prisoners with their lips stitched together, leaving enough space to take in liquids, but not enough to eat food. Some prisoners used strands of coarse fiber or pieces of wire.
A 22-year-old, who gave his name only as Yevgeny, said awkwardly through his constricted lips that he was "suffering for justice."
But the facility's director, Mars Zhusupbekov, countered that the protest was a reaction to his own attempts to bring justice.
Zhusupbekov said he was appointed head of the facility in the capital Bishkek last month and soon learned that a group of 23 inmates was allowed to roam the prison freely, extorting money from others.
"Intimidated prisoners would call their relatives and ask them to sell their apartment or car, and then transfer the money to the gang in jail," he said.
So Zhusupbekov said he decided to launch raids on cells in mid-January to stamp out the thugs. About a week later, inmates started to sew their lips together, an act he said was forced on frightened prisoners by the criminal gang in his facility.
Crime experts say prison gangs in former Soviet nations are typically part of a complex hierarchical fraternity that extends across the penitentiary system and is ultimately subservient to criminal leaders beyond jail walls.
Almost 400 prisoners bound their lips at Zhusupbekov's jail, and as many as 800 others are believed to have done the same in other jails in what they say is an act of solidarity. Authorities say it is only the influence of organized crime that could have enabled protests on such a large scale.
Zhusupbekov was sanguine about the lip-sewing, describing it as a similar procedure to piercing, and dismissed complaints about poor prison conditions. "This is not a hotel, this is not a holiday resort, they should serve their time," he said.
Prisoners said the raids were an attempt by Zhusupbekov to brutally assert his authority.
"We were just decorating our cell when they threw in a smoke grenade and then they beat us all," said Ulan Sheraliyev, who is awaiting trial on charges of robbery. "And so we are starving and demanding this not happen again and that the perpetrator be punished."
Since Soviet times, underfunded police and galloping corruption have enabled local mafia groups engaged in narcotics trafficking and other crimes to flourish and authorities say the writ of crime gangs extends deep into the nation's jails.
But State Correctional Service chairman Sheishenbek Bayzakov says the system was rotten from the top down.
"I fired 80 percent of prison directors, because over the past few years, they created corrupt schemes and forged alliances with the criminal world," said Bayzakov, who appointed to the post last year. "They laundered money and instead of buying normal food, they would buy rotten and expired goods and just kept the money for themselves."
Bayzakov said several former penitentiary directors now face prosecution for alleged crimes that include running the prison drug trade.
The protests in Kyrgyzstan's prisons have caused international alarm.
Matteo Mecacci, chair of the human rights committee of the Organization for Security and Cooperation in Europe's parliamentary assembly, issued a statement in the past week calling for an easing of conditions in detention facilities.
Reforming the country's jails is seen as an urgent priority by President Almazbek Atamabayev's government, which is battling to maintain stability in the face of opposition from political rivals and organized crime syndicates.
Atambayev was elected last year amid vows he would rid the country of corruption, which prospered under former leader Kurmanbek Bakiyev. Bakiyev was thrown out of power in a violent street uprising in April 2010.
Signs of unrest are viewed with deep apprehension in the West because Kyrgyzstan hosts a U.S. air base that serves as an important transportation hub for military operations in nearby Afghanistan.
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?Make thousands stuffing envelopes!? Unique work at home business opportunity!?

It?s statements like these which often lead to bogus business opportunities that have spurred the U.S. Federal Trade Commission into taking action to protect people who think they?re buying a legitimate business. Called the Business Opportunity Rule, this new requirement states that any individual who sells a business opportunity to another is required to disclose more information than in the past.
A business opportunity is simply a comprehensive business investment that lets the buyer start a business immediately. It?s ?out of the box,? so to speak. It?s different from a franchise.? A franchise is a business opportunity, but not all?business opportunities?are franchises, says Joel Libava, author of Become a Franchise Owner.
?Sometimes, people confuse a franchise business opportunity with a business opportunity, or bizopp. The major differences include upfront costs, (which are almost always significantly lower with a bizopp) support, and? the rules. In a business opportunity, there aren?t that many rules to follow as an owner. Business opportunities are generally looser in nature; you buy the opportunity, learn how to run the business, and then you?re pretty much free to market it and run it as you wish.?
What?s Required if You SELL Business Opportunities to Others
Anyone selling a business opportunity or bizopp must now provide information on a one-page disclosure document (PDF file)?at least seven days before the buyer pays money or signs a document. The seller must state the following:
Because of the rising number of business opportunity scams over the past few years, the FTC wanted to step up the measures taken to ensure the safety of buyers.
If you?re selling a business opportunity, understand that this new rule is meant to help you and the buyer perform a smooth transaction. Here are some tips to minimize the stress on your end:
What You Need to Know if You Are BUYING a Business Opportunity
If you are buying or considering buying a business opportunity, then know that the Business Opportunity Rule is to designed to help protect you from potentially bogus deals. Armed with the information the seller is required to give you, you should be able to get a better sense of whether a deal is legitimate. If it?s not, you now have ammunition for legal proceedings.
Pay attention to the earnings claims. In the past, companies have claimed that you could retire off of what you make stuffing envelopes, or make thousands of dollars off a work from home opp. These claims must now be substantiated in writing, and the buyer must list how much other buyers have made, and where they were located (since results may vary depending on many factors).
?The revised Business Opportunity Rule is long overdue,? says Libava, ?The most positive change has to do with research. Business opportunity buyers will now have access to a list provided by the business opportunity seller of at least 10 people who have bought their business opportunity. And, if fewer than 10 people have bought the business opportunity, every person that?s bought it must be listed.?
Libava says that buyers should know that they will have to sign a document stating that the buyer can share their personal contact information with future buyers.
Here are more tips to ensure you find a trustworthy business opportunity from the Business Opportunity blog:
You can read the complete Business Opportunity Rule document on the FTC website. The Rule will go into effect March 1, 2012.
Envelopes Photo via Shutterstock
Source: http://smallbiztrends.com/2012/01/ftc-business-opportunity-rule-what-it-means.html
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ScienceDaily (Jan. 26, 2012) ? Japan used seawater to cool nuclear fuel at the stricken Fukushima-Daiichi nuclear plant after the tsunami in March 2011 -- and that was probably the best action to take at the time, says Professor Alexandra Navrotsky of the University of California, Davis.
But Navrotsky and others have since discovered a new way in which seawater can corrode nuclear fuel, forming uranium compounds that could potentially travel long distances, either in solution or as very small particles. The research team published its work Jan. 23 in the Proceedings of the National Academy of Sciences.
"This is a phenomenon that has not been considered before," said Alexandra Navrotsky, distinguished professor of ceramic, earth and environmental materials chemistry. "We don't know how much this will increase the rate of corrosion, but it is something that will have to be considered in future."
Japan used seawater to avoid a much more serious accident at the Fukushima-Daiichi plant, and Navrotsky said, to her knowledge, there is no evidence of long-distance uranium contamination from the plant.
Uranium in nuclear fuel rods is in a chemical form that is "pretty insoluble" in water, Navrotsky said, unless the uranium is oxidized to uranium-VI -- a process that can be facilitated when radiation converts water into peroxide, a powerful oxidizing agent.
Peter Burns, professor of civil engineering and geological sciences at the University of Notre Dame and a co-author of the new paper, had previously made spherical uranium peroxide clusters, rather like carbon "buckyballs," that can dissolve or exist as solids.
In the new paper, the researchers show that in the presence of alkali metal ions such as sodium -- for example, in seawater -- these clusters are stable enough to persist in solution or as small particles even when the oxidizing agent is removed.
In other words, these clusters could form on the surface of a fuel rod exposed to seawater and then be transported away, surviving in the environment for months or years before reverting to more common forms of uranium, without peroxide, and settling to the bottom of the ocean. There is no data yet on how fast these uranium peroxide clusters will break down in the environment, Navrotsky said.
Navrotsky and Burns worked with the following co-authors: postdoctoral researcher Christopher Armstrong and project scientist Tatiana Shvareva, UC Davis; May Nyman, Sandia National Laboratory, Albuquerque, N.M.; and Ginger Sigmon, University of Notre Dame. The U.S. Department of Energy supported the project.
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In his last State of the Union address before the 2012 election, President Obama called upon Congress to work together to rebuild the coveted American Dream.
Our 44th President promised, in a memorable phrase, “no bail-outs, no hand-outs, no cop-outs” to financial institutions that helped derail the U.S. economy.
Obama spoke about “fair” tax reform with a thinly-veiled reference to phrases Republican presidential candidates have used against him repeatedly in debates.
“You can call this ‘class warfare’ all you want,” he said, calling it pure fairness. Without a doubt, the 2012 State of the Union address was a campaign speech:
He said Americans must get past personal ambition and partisan obsession to "focus on the mission at hand" and keep the dream alive by restoring the economy.
"No challenge is more urgent. No debate is more important," he said.
"We can either settle for a country where a shrinking number of people do really well, while a growing number barely get by. Or we can restore an economy where everyone gets a fair shot, everyone does their fair share and everyone plays by the same rules."
"Do we want to keep tax cuts for the wealthiest Americans? Or do we want invest in everything else? If we're serious about paying down our debt, we can't do both."
Rebuttals came quickly and predictably from political opponents.
Indiana Gov. Mitch Daniels, who delivered the "official" GOP response, said that the president's rigid adherence to ideology was suffocating innovation:
"Extremism that stifles development of homegrown energy, or cancels a perfectly safe pipeline that would employ tens of thousands, or jacks up consumer utility bills for no improvement in either human health or world temperature, is a pro-poverty policy."
"We do not accept that ours will ever be a nation of haves and have nots; we must always be a nation of haves and soon to haves," Daniels said.
On Fox News, Sean Hannity interviewed GOP candidate Mitt Romney, who asserted that, on the basis of this night, the President is “disconnected from reality.”
The bipartisan high point of the evening occurred just before the speech, as Obama, in making his way to the podium, paused to hug Rep. Gabrielle Giffords.
Giffords is resigning from Congress this week to recover from her brain injury. A chant of “Gabby, Gabby, Gabby” could be heard throughout the House floor.
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DORAL, Fla. ? Republican presidential candidate Newt Gingrich on Wednesday ridiculed rival Mitt Romney's call for self-deportation of illegal immigrants as an "Obama-level fantasy" that would be inhumane to long-established families living in America. Romney, for his part, accused Gingrich of pandering to a Hispanic audience and said Gingrich himself had supported self-deportation in the past.
Discussing immigration in state where 13 percent of registered voters are Hispanic, the former House speaker criticized Romney's immigration policy during a forum with the Spanish-language television network Univision, saying the idea of self-deportation would never work. Romney snapped back at him later in the day at the same forum.
During a debate earlier this week, Romney said he favors self-deportation over policies that would require the federal government to round up millions of illegal immigrants and send them back to their home countries. Advocates of Romney's approach argue that illegal immigration can be curbed by denying public benefits to them, prompting them to leave the United States on their own.
"You have to live in a world of Swiss bank accounts and Cayman Island accounts and automatically $20 million income for no work to have some fantasy this far from reality," Gingrich said, alluding to details in Romney's income tax returns made public Tuesday. "For Romney to believe that somebody's grandmother is going to be so cut off that she is going to self-deport, I mean this is an Obama-level fantasy."
But Gingrich's campaign has spoken of the self-deportation policy he ridiculed Wednesday.
"I recognize that it's very tempting to come out to an audience like this and pander to the audience," Romney said, pointing out that Gingrich has previously made comments supporting the idea of self-deportation. "I think that was a mistake on his part."
In debates, Gingrich has defended a proposal to allow some illegal immigrants to stay in the U.S. if they've lived here for more than 25 years and have a local sponsor.
Romney's campaign directed reporters to past comments by Gingrich spokesman R.C. Hammond, who said that only a small percent of illegal immigrants would likely be allowed to stay in the U.S. under Gingrich's plan. Hammond went on to say that the vast majority of them would likely "self-deport."
Gingrich also ran into trouble over a radio ad calling Romney "anti-immigrant." Florida Sen. Marco Rubio called the ad "inaccurate" and "inflammatory." Romney's campaign also asked Gingrich in a letter to pull the ad. Gingrich's campaign had no immediate comment on whether it would comply with the request to pull the ad. The Miami Herald reported that the campaign planned to remove the ad based on Rubio's comments.
Romney called the anti-immigrant label an "epithet" and "inappropriate."
At the forum, Gingrich spoke instead about other elements of his immigration plan, including controlling the border and establishing a guest-worker program to better manage the influx of immigrants. Gingrich said he favors a path to citizenship for illegal immigrant children who serve in the military but not for simply completing college.
Romney defended his opposition to allowing the children of illegal immigrants to pay in-state tuition at American universities. He said there are inexpensive options that will allow them to go to college.
Gingrich told Univision he believes states should charge in-state tuition rates for students who were born in the U.S. to illegal immigrant parents, but that he favors charging out-of-state tuition for children who were brought to this country illegally.
Texas Gov. Rick Perry's support of a Texas policy to allow children of illegal immigrants to pay in-state tuition proved to be problematic with conservatives nationwide. Perry dropped out of the race last week.
Gingrich began the interview by speaking a few halting phrases of welcome in Spanish ? "Buenos Dias estudiantes" ? but begged off when moderator Jorge Ramos pressed him to go further. Romney did not speak any Spanish during his interview.
Romney was asked about family members he has living in Mexico. Romney's father, George Romney, was born in Mexico but moved back to the U.S. as a young child.
Ramos asked Romney if he had a claim to being Mexican American.
"I don't think people would think I was being honest with them if I said I was Mexican American but I'd appreciate it if you'd get that word out," Romney said, smiling.
Florida is home to many Hispanics of Puerto Rican or Cuban descent who don't view immigration as a priority but are more interested in the issue than the general public.
After the interview, Romney railed against Fidel Castro's Cuba in a speech before several hundred Cuban-American democracy activists. Romney has significant support from the Cuban-American political establishment in Miami.
"It is time for us to strive for freedom in Cuba, and I will do so as president," he said. "We must be prepared to support the voices for democracy in Cuba."
While the interview questions asked of both candidates were mostly about Hispanic concerns, Ramos asked Gingrich whether it was hypocritical for him to criticize then-President Bill Clinton and pursue his impeachment in the 1990s when Gingrich was being unfaithful to his second wife.
Gingrich snapped at the premise of the question and said it was Clinton's false testimony under oath that bothered him the most.
"The fact is I've been through two divorces. I've been deposed both times under oath. Both times I told the truth in the deposition," Gingrich said. "I have never lied under oath. I have never committed perjury."
Ramos asked Romney to declare his wealth, to which Romney replied that he's worth between $150 million and "200-and-some-odd million dollars."
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PARIS ? European leaders' hard line in negotiations with Greek bondholders drove stock markets lower on Tuesday as investors worried that a deal necessary to cut Athens' mountain of debt might fall through.
After 10 hours of talks on Monday, the finance ministers of the countries that use the euro announced that Greece would pay less than 4 percent interest on the new bonds creditors will get in a swap meant to cut Greece's debt by about euro100 billion ($130 billion).
The deal is crucial to Greece's and the eurozone's stability since it's clear there's no way Athens can ever pay back all that it owes. Banks that hold Greek debt have already been asked to take a 50 percent loss on those investments ? and some think even that writedown isn't big enough.
The negotiations involve a delicate balancing act between getting a deal large enough to ensure that Greece can someday dig out from under its pile of debts but not so harmful to banks that it scares investors off from investing in any eurozone debt.
European leaders have promised Greece is a special case and bondholders won't ever be asked to take losses again, but there are signs that investors are staying clear of the bonds of other vulnerable countries, like Portugal.
Time is running out for politicians and the banks to get it right ? Greece has several billions of euros of debt coming due in March ? and stocks dropped Tuesday amid worries they might not.
In France, the CAC-40 fell 0.8 percent to 3,312, while Germany's DAX dropped 1 percent at 6,370. The FTSE index of leading British shares was down 0.7 percent to 5,740.
Wall Street was also set to open lower. Dow futures fell 0.3 percent at 12,609 and S&P futures dropped 0.4 percent to 1,305.
The euro fell 0.2 percent to $1.3000.
Politicians are also aware that European banks are under tremendous pressure because of the amount of government debt they hold and have seen their stock prices crash and their sources of funding dry up during the crisis. Late Monday, Standard & Poor's downgraded the credit ratings of two major French banks, Credit Agricole and Societe Generale. They confirmed the rating of a third major bank, BNP Paribas, but the stock prices of all three plummeted Tuesday, underscoring how fragile all financial institutions are.
Compounding these concerns is the poor state of Europe's economy and worries that the eurozone is slipping back into recession. Even relatively positive results from two economic surveys released Tuesday were not enough to ease those worries.
January's manufacturing purchasing managers' composite index rose to 48.7 from 46.9, according to Markit, a financial data company. The services PMI rose to 50.5 from 48.8. Both surveys, which are considered indicators for growth, beat the expectations of analysts, but experts warned they are far from good news.
"While the January purchasing managers' surveys lift hopes that eurozone activity is stabilizing, they also suggest that the eurozone is far from out of the economic woods," said Howard Archer, an analyst with IHS Global Insight. "Worrying elements remain in the purchasing managers' surveys and we suspect that it is still more likely than not that the eurozone will suffer further contraction in the first quarter of 2012 which will put it back into recession."
Concerns about the state of economy even tempered oil prices, which had been skyrocketing after European leaders announced they would stop buying Iranian oil in an effort to pressure Tehran into resuming talks on its nuclear program.
Benchmark oil fell back 30 cents to $99.28 in electronic trading on the New York Mercantile Exchange.
Earlier in Asia, Japan's Nikkei 225 stock rose 0.2 percent to 8,785.33 despite the central bank cutting growth forecasts for the fiscal year ending March 2012 and the following year because of a slowdown in overseas demand and the strong yen.
Australia's S&P/ASX 200 closed little changed at 4,224.20. Indonesia's benchmark was up 0.1 percent at 3,994.91 and India's Sensex was 1.5 percent higher at 16,997.35 after the Reserve Bank of India lowered cash reserve requirements for commercial lenders.
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Contact: Karen Mallet
km463@georgetown.edu
Georgetown University Medical Center
WASHINGTON, DC A Georgetown University Medical Center professor says the voluntary action taken by two research teams to temporarily halt work involving the highly pathogenic avian influenza H5N1 is "laudable."
In the researchers' statement, published today by Science and Nature, the authors stated that they "recognize that we and the rest of the scientific community need to clearly explain the benefits of this important research and the measures taken to minimize its possible risks." The statement comes in the wake of a debate following the U.S. government's request that Science and Nature withhold scientific information related to the genetically modified H5N1 virus because of biosecurity concerns.
"This is a laudable decision to make sure that all voices are heard on such an important issue," says John D. Kraemer, JD, MPH, assistant professor of health systems administration at Georgetown University School of Nursing & Health Studies. Trained in both public health and the law, Kraemer conducts scholarship on public health law and ethics, with a particular focus on the ethical and legal limits of governmental action to address health concerns.
"The moratorium will provide an opportunity for institutions to assess the best way of overseeing dual use research that which has both significant potential for public health benefits and a chance for harm," he adds.
In 2011, two research teams one from the United States and one from the Netherlands announced that they had genetically modified the H5N1 avian influenza virus in such a way that it could possibly spread rapidly among humans. They estimated that half of those who would contract the engineered virus would die (the research was conducted in an animal model believed to represent human behavior of the virus). Their work, funded by the National Institutes of Health (NIH), was submitted independently to the journals Nature and Science for publication. The National Science Advisory Board for Biosecurity (NSABB), which advises the Department of Health and Human Services (HHS), recommended that Science and Nature redact key information prior to publication out of concern that published details about the papers' methodology and results could become a blueprint for bioterrorism.
On January 19, Kraemer and his colleague, Lawrence O. Gostin, the Linda D. and Timothy J. O'Neill Professor of Global Health Law at Georgetown University Law Center, published an invited opinion on the topic for Science's "Policy Forum." ("The Limits of Government Regulation of Science" 19 Jan 2012).
In it, Kraemer and Gostin said the U.S. government's request that the journals Science and Nature withhold that scientific information does not violate the First Amendment. They advised, however, that a fair, transparent process undertaken by research organizations is preferable to governmental constraints on disseminating scientific information.
"The NSABB process seems to have worked well in this instance," says Kraemer. "It raised legitimate security concerns while avoiding censorship of the scientific press. But there remains a need to strengthen precautions around this type of research before scientific censorship occurs."
###
About Georgetown University Medical Center
Georgetown University Medical Center is an internationally recognized academic medical center with a three-part mission of research, teaching and patient care (through MedStar Health). GUMC's mission is carried out with a strong emphasis on public service and a dedication to the Catholic, Jesuit principle of cura personalis -- or "care of the whole person." The Medical Center includes the School of Medicine and the School of Nursing & Health Studies, both nationally ranked; Georgetown Lombardi Comprehensive Cancer Center, designated as a comprehensive cancer center by the National Cancer Institute; and the Biomedical Graduate Research Organization (BGRO), which accounts for the majority of externally funded research at GUMC including a Clinical Translation and Science Award from the National Institutes of Health. In fiscal year 2010-11, GUMC accounted for 85 percent of the university's sponsored research funding.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Contact: Karen Mallet
km463@georgetown.edu
Georgetown University Medical Center
WASHINGTON, DC A Georgetown University Medical Center professor says the voluntary action taken by two research teams to temporarily halt work involving the highly pathogenic avian influenza H5N1 is "laudable."
In the researchers' statement, published today by Science and Nature, the authors stated that they "recognize that we and the rest of the scientific community need to clearly explain the benefits of this important research and the measures taken to minimize its possible risks." The statement comes in the wake of a debate following the U.S. government's request that Science and Nature withhold scientific information related to the genetically modified H5N1 virus because of biosecurity concerns.
"This is a laudable decision to make sure that all voices are heard on such an important issue," says John D. Kraemer, JD, MPH, assistant professor of health systems administration at Georgetown University School of Nursing & Health Studies. Trained in both public health and the law, Kraemer conducts scholarship on public health law and ethics, with a particular focus on the ethical and legal limits of governmental action to address health concerns.
"The moratorium will provide an opportunity for institutions to assess the best way of overseeing dual use research that which has both significant potential for public health benefits and a chance for harm," he adds.
In 2011, two research teams one from the United States and one from the Netherlands announced that they had genetically modified the H5N1 avian influenza virus in such a way that it could possibly spread rapidly among humans. They estimated that half of those who would contract the engineered virus would die (the research was conducted in an animal model believed to represent human behavior of the virus). Their work, funded by the National Institutes of Health (NIH), was submitted independently to the journals Nature and Science for publication. The National Science Advisory Board for Biosecurity (NSABB), which advises the Department of Health and Human Services (HHS), recommended that Science and Nature redact key information prior to publication out of concern that published details about the papers' methodology and results could become a blueprint for bioterrorism.
On January 19, Kraemer and his colleague, Lawrence O. Gostin, the Linda D. and Timothy J. O'Neill Professor of Global Health Law at Georgetown University Law Center, published an invited opinion on the topic for Science's "Policy Forum." ("The Limits of Government Regulation of Science" 19 Jan 2012).
In it, Kraemer and Gostin said the U.S. government's request that the journals Science and Nature withhold that scientific information does not violate the First Amendment. They advised, however, that a fair, transparent process undertaken by research organizations is preferable to governmental constraints on disseminating scientific information.
"The NSABB process seems to have worked well in this instance," says Kraemer. "It raised legitimate security concerns while avoiding censorship of the scientific press. But there remains a need to strengthen precautions around this type of research before scientific censorship occurs."
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About Georgetown University Medical Center
Georgetown University Medical Center is an internationally recognized academic medical center with a three-part mission of research, teaching and patient care (through MedStar Health). GUMC's mission is carried out with a strong emphasis on public service and a dedication to the Catholic, Jesuit principle of cura personalis -- or "care of the whole person." The Medical Center includes the School of Medicine and the School of Nursing & Health Studies, both nationally ranked; Georgetown Lombardi Comprehensive Cancer Center, designated as a comprehensive cancer center by the National Cancer Institute; and the Biomedical Graduate Research Organization (BGRO), which accounts for the majority of externally funded research at GUMC including a Clinical Translation and Science Award from the National Institutes of Health. In fiscal year 2010-11, GUMC accounted for 85 percent of the university's sponsored research funding.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2012-01/gumc-gpa012312.php
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LOS ANGELES ? Kate Beckinsale is back with a vengeance, with her latest "Underworld" movie opening at No. 1 this weekend.
"Underworld Awakening" made an estimated $25.4, distributor Sony Screen Gems reported Sunday.
This is the fourth film in the vampire action saga. Beckinsale starred in the first two movies as the warrior Selene, then bowed out of part three but returned for this latest installment. "Underworld Awakening" was shown for the first time in 3-D as well as on IMAX screens, where it made $3.8 million. That's 15 percent of the film's weekend gross, which is a record for an IMAX digital-only run.
Sony had hoped the film would end up in the low-$20 million range. But Rory Bruer, the studio's president of worldwide distribution, says the fact that it did even better ? despite a snow storm that hit much of the Midwest and East Coast ? primarily has to do with Beckinsale's return.
"She is such a force. Her character ? you just can't take your eyes off of her. I know the character is very dear to her, as well, and she just kills it," Bruer said. "The 3-D aspect of the film also brings something, makes it a fun, visceral ride."
Opening in second place was "Red Tails" from executive producer George Lucas, about the Tuskegee Airmen who were the first black fighter pilots to serve in World War II. It made an estimated $19.1 million, according to 20th Century Fox, which was well above expectations; the studio had hoped to reach double digits, said Chris Aronson, executive vice president of domestic distribution.
"I believe what George Lucas has stated all along: This is an important story and a story that must be told. It is a true story of American heroism and valor and audiences have really responded to this message," Aronson said. "People want to feel good about themselves, they want to be uplifted. We have enough hard crud going on in this country right now. Times are tough, and if we look back and are told a story of some really fantastic deeds, that's really compelling moviegoing."
Hollywood.com analyst Paul Dergarabedian said a grass-roots effort to get groups of people into the theaters to see "Red Tails," along with positive word-of-mouth, helped its strong showing. The film saw an uptick from about $6 million on Friday to $8.65 on Saturday.
Overall box office is up 31 percent from the same weekend a year ago, Dergarabedian said, thanks to new releases as well as movies like "Extremely Loud & Incredibly Close," which had limited runs for awards consideration at the end of 2011 and are now expanding nationwide. The 9/11 drama from Warner Bros., starring Tom Hanks and Sandra Bullock, came in fourth place with $10.5 million.
Last week's No. 1 film, the Universal smuggling thriller "Contraband" starring Mark Wahlberg, dropped to the No. 3 spot with $12.2 million. It's now made $46.1 million in two weeks. Meanwhile, Steven Soderbergh's international action picture "Haywire" from Relativity Media, starring mixed martial arts superstar Gina Carano in her first film role, opened in fifth place with $9 million, which was above expectations.
"This is a great, perfect January weekend. You've got these holdover films and newcomers creating an overall marketplace that people are really responding to," Dergarabedian said. "It sounds clich? but this marketplace really has something for everyone."
As for worldwide box office, "The Twilight Saga: Breaking Dawn ? Part 1" has now crossed the $700 million mark. The first half of the finale of the girl-vampire-werewolf love triangle franchise has grossed an estimated $701.3 million in global box office receipts since its release last November, according to Lionsgate, which recently acquired Summit Entertainment, which distributes the series.
Estimated ticket sales for Friday through Sunday at U.S. and Canadian theaters, according to Hollywood.com. Where available, latest international numbers are also included. Final domestic figures will be released Monday.
1. "Underworld Awakening," $25.4 million ($13.4 million international).
2. "Red Tails," $19.1 million.
3. "Contraband," $12.2 million.
4. "Extremely Loud & Incredibly Close," $10.5 million.
5. "Haywire," $9 million.
6. "Beauty and the Beast (3-D)," $8.6 million.
7. "Joyful Noise," $6.1 million.
8. "Mission: Impossible ? Ghost Protocol," $5.5 million. ($9.4 million international).
9. "Sherlock Holmes: A Game of Shadows," $4.8 million. ($18.1 million international).
10. "The Girl With the Dragon Tattoo," $3.75 million ($15.7 international).
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Estimated weekend ticket sales at international theaters (excluding the U.S. and Canada) for films distributed overseas by Hollywood studios, according to Rentrak:
"Sherlock Holmes: A Game of Shadows," $18.1 million.
"The Girl With the Dragon Tattoo," $15.7 million.
"Underworld Awakening," $13.4 million.
"Mission: Impossible ? Ghost Protocol," $9.4 million international.
"Alvin and the Chipmunks: Chipwrecked," $9.3 million.
"Puss in Boots," $8.7 million.
"Journey 2: The Mysterious Island," $8.2 million.
"War Horse," $7.3 million.
"The Descendants," $6.2 million.
"The Darkest Hour," $5.1 million.
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Online:
http://www.hollywood.com
http://www.rentrak.com
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AP Movie Writer Christy Lemire can be reached at http://www.twitter.com/christylemire/
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By Rosa Golijan

I hope your torches and pitchforks aren't nearby, because Google ??the Company That Claims It Does No Evil ??is doing something that might make you want to reach for 'em. Apparently the search engine giant is now forcing new Google account users to join Google+ and Gmail.
Google Operating System, an unofficial blog about all things Google, first called attention to this somewhat annoying requirement for new Google accounts?? which most certainly wasn't always in effect:
Until now, creating a Google account was quite simple. You could either use an existing email address or create a Gmail account.
The newly redesigned sign-up process for Google accounts now includes?fields which ask for your name, gender (required, thanks to Google+) and mobile phone number (optional).?Once you've got those fields filled out, you're led to a page which asks you to create your Google profile ??better known as your Google+ account.
There is no option to skip this step and avoid the creation of a Google+ account (and a Gmail account), which is something you might want to do if you're interested in using only some other Google services.
The only choice you have if you want to avoid Google+ or Gmail, as Google Operating System points out, is to create a Google Account through the Google Calendar or Blogger pages ??or by going to a URL which corresponds to the old sign-up form. Unfortunately there's no way of knowing just how long this workaround will continue to work.?
Related stories:
Want more tech news, silly puns or amusing links? You'll get plenty of all three if you keep up with Rosa Golijan, the writer of this post, by following her on?Twitter, subscribing to her?Facebook?posts, or circling her?on?Google+.
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DETROIT/TOKYO (Reuters) ? General Motors Co (GM.N) regained its title as the world's top-selling automaker in 2011, less than three years after its 2009 taxpayer-funded bankruptcy under the Obama administration.
The Detroit-based automaker's return to the top slot comes as Japanese rival and former No. 1 seller Toyota Motor Corp (7203.T) slips in the rankings after an earthquake in Japan and deadly floods in Thailand hampered its production in 2011.
GM said it sold 9.026 million vehicles globally last year, up 7.6 percent from 2010.
Volkswagen AG (VOWG_p.DE), the German company vying to become the world's largest carmaker, finished the year in second place with 8.16 million vehicles sold.
Toyota will publish its final sales results for 2011 later this month but has projected sales of 7.9 million in 2011, down about 6 percent from a year earlier.
The tabulation of global auto sales is not without controversy. Rankings are mostly about bragging rights, but there has been a long-running and robust debate over how to account for vehicles sold through affiliates.
The sales figures released by GM, which was the largest automaker until 2008 when Toyota took its place, include vehicles sold through its joint ventures in China. Some analysts extract those sales from GM's results.
Depending on how the results are tallied, Toyota may have finished the year in third place. However, Toyota would fall to fourth place behind Renault SA (RENA.PA) and its partner Nissan Motor Co (7201.T) if the alliance's sales through Russia's AvtoVAZ (AVAZ.MM) are included.
Including AvtoVAZ, Renault-Nissan sold 8.03 million cars worldwide last year. This includes the 638,000 cars sold by AvtoVAZ, in which Renault owns a minority 25 percent.
The International Organization of Motor Vehicle Manufacturers, a global trade group based in France, has not yet released its annual ranking of automakers by production.
TOYOTA MOUNTS COMEBACK
Toyota's 2011 worldwide sales tally included listed subsidiaries Daihatsu Motors Co (7262.T) and Hino Motors Ltd (7205.T).
Toyota's sales were hurt by a series of disasters that triggered auto parts shortages and curtailed its vehicle production last year.
But now Toyota is ramping up production to rebuild depleted inventory and will add output capacity in emerging markets such as Brazil and China this year. However, analysts said it also faced stiffer competition as rivals step up their game.
"Toyota's biggest problem is that even without the natural disasters, its sales weren't exactly growing," JP Morgan auto analyst Kohei Takahashi said.
"The ranking is not that important, but they need a convincing strategy to boost their sales," he said, adding that Toyota was behind rivals such as Nissan in rolling out small cars for emerging markets.
Toyota has lagged the sharper sales growth at rivals such as Nissan and Hyundai Motor Co (005380.KS) because of a relatively slow push into emerging markets as it scrambled to meet runaway demand in mature markets in the past decade.
In a bid to catch up, Toyota is adding factories in Brazil, China, Thailand and elsewhere, aiming to sell half its cars in emerging markets by 2015, up from around 40 percent now.
South Korean sister carmakers Hyundai Motor Co (005380.KS) and its 34 percent owned Kia Motors Corp (000270.KS) racked up total sales of 6.53 million last year.
(Reporting by Deepa Seetharaman in Detroit, Chang-Ran Kim in Tokyo; Editing by Mark Bendeich)
Source: http://us.rd.yahoo.com/dailynews/rss/business/*http%3A//news.yahoo.com/s/nm/20120120/bs_nm/us_gm
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LOS ANGELES ? Microsoft Corp. battled through a weak PC market to post flat earnings in the final quarter of 2011, boosting sales of servers, Xbox games and its Office productivity software while trimming losses at its Bing search engine.
Net income in the company's second quarter through December came to $6.62 billion, down slightly from the $6.63 billion a year ago. Earnings per share came to 78 cents, up a penny from a year ago, as the outstanding share count fell.
Revenue rose 5 percent to $20.89 billion.
The earnings reported after the close of trading on Wall Street Thursday beat expectations of analysts polled by FactSet, who were looking for 76 cents per share. But sales were below the $20.92 billion expected.
Microsoft's shares rose 54 cents, or 1.9 percent, to $28.66 in after-hours trading.
Colin Gillis, an analyst with BGC, said cost controls and a second-consecutive quarter of reducing losses at Bing helped results. Continuing growth in its Office software division was also encouraging, while the decline in the PC market and its negative impact on the flagship Windows operating system was expected.
"People were afraid it was going to be much, much worse," he said.
Company watchers had been concerned that a shortage of hard disk drives from flood-ravaged Thailand would hit PC sales and hurt sales of the world's most-used operating system, Windows. Microsoft's position as a leading operating system maker is also facing challenges as people use more tablet computers like Apple Inc.'s iPad and mobile devices using Google Inc.'s Android system.
Microsoft is looking ahead to the release of Windows 8, an operating system that should operate similarly over PCs and mobile devices. A beta version is due out next month.
CEO Steve Ballmer, in a statement, called the quarter's results solid even as the company "prepares for a launch year that will accelerate many of our key products and services."
He said that the company has gotten positive reviews of its Metro style design that will unify the way consumers interact with Windows-based phones, computers, tablets and even televisions this year.
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NEW YORK ? Stocks rose in midday trading Thursday after a decline in applications for unemployment benefits and strong earnings reports from Bank of America and Morgan Stanley.
The Dow Jones industrial average rose 35 points to 12,613 shortly after noon.
The number of people seeking unemployment benefits plunged last week to the lowest level since April 2008, the latest sign that the job market is strengthening. France and Spain also held successful bond auctions, easing worries about that region's two-year-old debt crisis.
Utilities companies were among the few industries to fall, an indication that investors are becoming more comfortable owning riskier stocks. Utilities, which were the best-performing industry last year, tend to pay higher dividends and fluctuate less than companies like Caterpillar Inc. and FedEx Corp., whose fortunes are more closely tied to the economic cycle. Financial technology companies each rose 1 percent, the most of the 10 industries tracked by the S&P 500 index.
In another sign that investors are shedding low-risk assets, the dollar and Treasury prices fell. The yield on the benchmark 10-year Treasury note rose to 1.97 percent from 1.90 percent late Wednesday.
Bank of America and Morgan Stanley each rose 5 percent after reporting results that were better than analysts had expected. BofA returned to profit in the fourth quarter while Morgan Stanley's loss was much less than forecast, thanks largely to better stock trading results.
Investors also drove up shares of Renewable Energy Group Inc., the nation's largest producer of biodiesel, in its market debut. The stock rose 1 percent after pricing below what the Iowa company had initially expected. It was the first initial public offering of the year.
Trading was halted in shares of photography icon Eastman Kodak after the company filed for Chapter 11 bankruptcy protection. The ailing company failed to find a buyer for its trove of 1,100 digital imaging patents.
In other trading, the Standard & Poor's 500 rose 7 points, or 0.5 percent, to 1,315. The Nasdaq composite rose 23 points, or 0.9 percent, to 2,793.
Among other stocks making large moves:
? eBay Inc. rose more than 4 percent after the online auction company beat analysts' earnings forecasts and provided a healthy outlook for the year.
? Southwest Airlines Co. rose nearly 4 percent after it said its fourth-quarter net income and revenue jumped. Southwest said it expects strong revenue in the first quarter too, based on passenger-booking trends.
? Johnson Controls Inc., an auto parts and building equipment maker, fell 7 percent. The Milwaukee-based company reported earnings and revenue that fell short of Wall Street's forecasts. It also cut its estimate for its fiscal year earnings, blaming weaker auto production in Europe, a lower euro and poor demand for batteries.
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| The average rate on the 30-year fixed mortgage fell to a record low of 3.88 percent, Freddie Mac said Thursday. That's just below the previous record of 3.89 percent reached one week ago. Here's a look at rates for fixed- and adjustable-rate mortgages over the past 52 weeks. |
| Current week's average Last week's average 52-week high 52-week low |
| 30-year fixed 3.88 3.89 5.05 3.88 |
| 15-year fixed 3.17 3.16 4.29 3.16 |
| 5-year adjustable 2.82 2.82 3.92 2.82 |
| 1-year adjustable 2.74 2.76 3.40 2.74 |
| All values are in percentage points. |
| Source: Freddie Mac Primary Mortgage Market Survey. |
Copyright ? 2012 The Associated Press. All rights reserved. The information contained in the AP News report may not be published, broadcast, rewritten or redistributed without the prior written authority of The Associated Press.
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